Spermidine Trihydrochloride 98% Powder High Purity Spermidine 3HCl CAS 334-50-9 Industrial Grade Bulk Supply
Product Detail
Product Tags
SPERMIDINE
TRIHYDROCHLORIDE
Our Spermidine Trihydrochloride (CAS 334-50-9) is produced through a standardized preparation process, ensuring an assay of ≥98.0% as verified by HPLC analysis. This crystalline salt form offers enhanced chemical stability and formulation compatibility compared to free-base alternatives. Through rigorous quality control, solvent residues are maintained within established regulatory limits, providing a consistent raw material for research-driven nutraceutical and pharmaceutical applications.
|
Assay: ≥98.0% (HPLC)
|
CAS: 334-50-9
|
C7H19N3·3HCl
|
|
|
|
|
Technical Specifications
Analytical Characterization
|
| Product Name |
Spermidine Trihydrochloride |
| CAS Registry No. |
334-50-9 |
| Molecular Identity |
C7H19N3 · 3HCl |
| Physical Form |
White Crystalline Powder |
| Solubility |
H2O: 50 mg/mL, clear, colorless |
| Storage Class |
Standard temperature; kept in a dry and cool place |
* This specification sheet is for informational purposes for professional laboratory use and manufacturing.
Full compendial testing (USP/EP) data is documented in the Batch Certificate of Analysis. |
Reference Grade
|
|
|
Technical Core Advantages
Material characterization & compliance
|
Analytical
Precision
Every batch undergoes rigorous HPLC analysis to ensure a standardized purity of ≥98.0%. We provide comprehensive documentation including COAs for heavy metals and microbial limits, ensuring total data traceability for biochemical research and high-end manufacturing.
|
Enhanced
Stability
The crystalline Trihydrochloride form offers superior shelf-stability compared to liquid alternatives. It exhibits low hygroscopicity and high resistance to oxidation at ambient temperatures, minimizing degradation risks during downstream processing and storage.
|
Regulatory
Compliance
Our production protocols strictly align with international quality standards. We maintain low solvent residues that comply with stringent European and North American regulatory benchmarks, facilitating seamless import clearance and regulatory approval.
|
Certificate of Analysis (COA)
| Product Name |
Spermidine Trihydrochloride |
Quantity |
500 kg |
| Batch No. |
DMTL260407 |
Test Date |
2026-04-08 |
| Manufacturing Date |
2026-04-07 |
Expiry Date |
2028-04-06 |
| Items |
Specification |
Methods |
Results |
| Color |
White |
GB1886.244-2016 |
Conformity |
| Form |
Powder |
GB1886.244-2016 |
Conformity |
| Assay |
≥98% |
GB1886.244-2016 |
98.62% |
| Loss on Drying |
≤5.0 (g/100g) |
GB1886.244-2016 |
1.94 |
| Ash content |
≤4.0 (%) |
GB1886.244-2016 |
0.10 |
| Arsenic (as As) |
≤2.0 (mg/kg) |
GB1886.244-2016 |
Conformity |
| Lead (as Pb) |
≤5.0 (mg/kg) |
GB1886.244-2016 |
Conformity |
| Shelf Life |
24 months under standard storage, no antioxidant used. |
| Package |
25 kg/carton outside and double food plastic bags inside. |
| Storage |
Store in a cool, dry place away from Moisture, Light, and Oxygen. |
|
|
Mechanism of Technical Function
Cellular Homeostasis & Regeneration Pathways
|
Induction of Autophagy
As a potent endogenous polyamine, Spermidine acts as a caloric restriction mimetic. It induces cellular autophagy by inhibiting the EP300 acetyltransferase, triggering the degradation and recycling of damaged organelles and misfolded proteins to maintain cellular proteostasis.
|
Translation Modulation
Spermidine is an essential cofactor for the hypusination of eIF5A (Eukaryotic Translation Initiation Factor 5A). This critical post-translational modification is vital for the efficient synthesis of specific proteins required for cell growth and mitochondrial function.
|
Genomic Integrity
Due to its polycationic nature at physiological pH, Spermidine binds to negatively charged DNA and phospholipids. This interaction helps stabilize chromatin structure and provides a molecular shield against oxidative damage induced by reactive oxygen species (ROS).
|
Note: The biochemical mechanisms described are based on current peer-reviewed research. This information is intended for technical professionals and researchers only.
|
|
Applications & Industries
Versatile integration in life sciences
|
-
| ▪ |
Cellular health and longevity support formulations (Capsules & Tablets). |
-
| ▪ |
Premium multi-ingredient complexes for metabolic homeostasis. |
-
| ▪ |
Stable crystalline ingredient for specialized powdered health supplements. |
|
-
| ▪ |
High-end skin repair serums and anti-aging topical formulations. |
-
| ▪ |
Follicle protection and hair density enhancement products. |
-
| ▪ |
Regenerative cosmetic additives focusing on cellular renewal. |
|
-
| ▪ |
Reference standard for autophagy-related in vitro studies. |
-
| ▪ |
Growth medium additive for high-fidelity cell culture systems. |
-
| ▪ |
Molecular biology investigations into polyamine metabolism. |
|
-
| ▪ |
Foundational building block for complex organic synthesis. |
-
| ▪ |
Starting material for stable hydrochloride-based derivatives. |
-
| ▪ |
Precursor for targeted drug delivery system research. |
|
|
|
Frequently Asked Questions
Technical support & logistics inquiries
|
Q1: What is the difference between the Salt form and the Free Base form?
Spermidine Trihydrochloride is a stabilized salt form of Spermidine. Compared to the liquid Free Base, which is highly oxidative, corrosive, and unstable, the Trihydrochloride crystalline form offers superior chemical stability, extended shelf-life, and excellent solubility, making it the preferred choice for solid formulations.
Q2: Does the product require cold chain transportation?
Based on stability stress testing, our Spermidine Trihydrochloride remains stable at ambient temperatures. We utilize moisture-proof and light-shielding packaging, standard international air freight does not require a cold chain.
Q3: Can you provide third-party test reports?
In addition to our internal Laboratory COA, we support and cooperate with customers for re-testing of purity, heavy metals, and solvent residues at recognized third-party analytical institutions (such as SGS or Eurofins) upon request.
Q4: What is the Minimum Order Quantity (MOQ)?
As a primary source supplier, we support projects from the early R&D stage. Sample MOQs start as low as 10g, while commercial order MOQs typically start at 1kg.
Professional Supply Chain & Services
Quality Certifications
Verified Organic, ISO, and Non-GMO standards for global compliance.
Custom OEM/ODM
Tailored formulation and branding solutions for your private label.
Secure Packaging
Professional grade multi-layer protection for long-distance transit.
Fast Global Delivery
Efficient logistics network providing reliable air and sea shipping.
Previous:
Organic Matcha Powder -Ceremonial Grade Matcha Green Tea Powder-Dual Certified EU & USDA Organic Matcha
Next:
