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Natural Plant-Derived Liposomal Apigenin Powder 50% 70% CAS 520-36-5

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Some of nature’s quietest gifts hide in the simplest places. Apigenin is one of them — a gentle flavonoid that gives chamomile tea its calming soul and lends celery its crisp, earthy character. Our liposomal apigenin powder brings this botanical wisdom into modern formulation: nature-identical apigenin wrapped within plant-derived phospholipids, presented as a clean powder at 50% or 70% active strength. Genuine plant heritage paired with modern liposomal science.


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BOTANICAL FLAVONOID INGREDIENT

Liposomal Apigenin

Some of nature’s quietest gifts hide in the simplest places. Apigenin is one of them — a gentle flavonoid that gives chamomile tea its calming soul and lends celery its crisp, earthy character. Our liposomal apigenin powder brings this botanical wisdom into modern formulation: nature-identical apigenin wrapped within plant-derived phospholipids, presented as a clean powder at 50% or 70% active strength. Genuine plant heritage paired with modern liposomal science.

CAS 520-36-5
50% & 70% Loading
Plant-Source Phospholipid
Clean Label Ready
Liposomal Apigenin Powder

SPECIFICATIONS
Product Name Liposomal Apigenin Powder
Active Ingredient Apigenin (CAS 520-36-5)
Botanical Origin Apium graveolens (Celery), Matricaria chamomilla (Chamomile), Petroselinum crispum (Parsley)
Active Loading Capacity 50% Standard Grade  |  70% High-Potency Grade
Encapsulation Efficiency (EE%) ≥ 80% (Typical)
Particle Size 80nm – 300nm (Rehydrated)
PDI ≤ 0.35
Appearance Light Yellow to Yellow-Green Powder
Solubility Dispersible in water (stable liposomal suspension)
Phospholipid Source Plant-Derived (Non-GMO)
Loss on Drying ≤ 5.0%
Heavy Metals (as Pb) ≤ 10 ppm
Storage Cool, dry environment; sealed container protected from light
Shelf Life Refer to batch-specific COA

THE APIGENIN STORY

Walk through a chamomile field at harvest, and the air carries a soft, honeyed fragrance. Hidden within those blossoms, and within the crisp green stalks of celery, is apigenin — a flavonoid that belongs to nature’s quiet class of protective plant compounds. Plants produce flavonoids for themselves — as pigments, UV shields, and chemical messengers — yet these same molecules interact with human biochemistry in ways nutritional science is still uncovering.

But apigenin shares a challenge with many beneficial flavonoids: it’s naturally lipophilic, meaning it doesn’t mix well with water. In a tea cup, that’s fine. In a supplement powder that needs to disperse evenly and release predictably, it’s a different story.

This is where liposomal technology enters — not as a synthetic fix, but as a biomimetic one. The same phospholipid bilayer structure that forms every living cell membrane becomes the carrier for apigenin. The flavonoid dissolves into the lipid layer; the phospholipids wrap around it like a microscopic protective envelope. Spray-dried into powder form, each particle carries apigenin within plant-derived lipids — ready to disperse in water and release gradually. From field to liposome, the journey honors apigenin’s botanical origins at every step.

Apigenin: From Field to Liposome

WHAT MAKES IT SPECIAL

1. Chamomile’s Signature Flavonoid

Apigenin is one of the bioactive compounds behind chamomile’s centuries-old reputation as a calming botanical. Our liposomal format preserves this natural identity while addressing apigenin’s solubility limitation — the same flavonoid your customers associate with chamomile tea’s gentle comfort, now in a form designed for reliable dispersion and gradual release.

2. Full Botanical Integrity

Unlike liposomal ingredients using animal-derived lecithin, our phospholipid carrier comes from plant lipids — keeping the entire delivery system aligned with vegan values and clean-label positioning. From the flavonoid core to the lipid shell, every component has a plant origin story.

3. Clean-Label Simplicity

Two components, nothing hidden: nature-identical apigenin + plant-derived phospholipids. No synthetic modifiers, no solvent residues, no controversial processing aids. This minimalist composition translates to transparent Supplement Facts panels and authentic brand storytelling.

4. Two Strengths, One Philosophy

The 50% grade serves accessible everyday-wellness formulations; the 70% grade powers premium high-potency botanical products. Both share the same plant-derived liposomal platform — brands can position across multiple price points while maintaining a consistent ingredient story.

CERTIFICATE OF ANALYSIS
Items Specification Methods Results
Assay (Apigenin) 50% / 70% HPLC 50.1% / 70.3%
Encapsulation Efficiency ≥ 80% Centrifugation-UV 83.5%
Particle Size (DLS) 80–300nm DLS 185nm
PDI ≤ 0.35 DLS 0.25
Appearance Light Yellow to Yellow-Green Powder Visual Conformity
Loss on Drying ≤ 5.0% Gravimetric 3.8%
Heavy Metals (as Pb) ≤ 10 ppm ICP-MS Conformity
Arsenic (As) ≤ 1 ppm ICP-MS Conformity
Cadmium (Cd) ≤ 1 ppm ICP-MS Conformity
Mercury (Hg) ≤ 0.1 ppm ICP-MS Conformity
TPC ≤ 1,000 CFU/g Plate Count Conformity
Yeast & Mold ≤ 100 CFU/g Plate Count Conformity
E. coli Negative / 25g USP <62> Conformity
Salmonella Negative / 25g USP <62> Conformity
Shelf Life Refer to batch-specific COA for exact expiry date.
Package & Storage 1kg/foil bag or 25kg/drum. Store cool, dry, dark, sealed below 25°C.

HOW WE MAKE IT
Manufacturing Process
1

Sourcing with Care

Apigenin active (HPLC-verified, ≥98% purity) and non-GMO plant-derived phospholipids sourced from qualified suppliers. Every incoming lot identity-tested before production.

2

Gentle Dissolution & Emulsification

Apigenin dissolved into phospholipid phase under controlled low-temperature conditions, then precision high-shear emulsified. Phospholipids self-assemble into bilayer vesicles — nature’s own transport mechanism.

3

Careful Spray-Drying

Emulsion spray-dried under optimized temperature profiles, preserving vesicle integrity while removing water. Each particle becomes a microscopic package of apigenin within plant-derived lipids.

4

Verification Before Release

HPLC assay, DLS particle sizing, EE% measurement, heavy metal screening, and microbial testing. Batch-specific COA issued only when all results meet specification.

WELLNESS BENEFITS

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Wellness Benefits

1. A Botanical Antioxidant

Apigenin belongs to the flavonoid family — plant compounds widely recognized for their antioxidant properties. In dietary supplements, it contributes to the total antioxidant capacity of botanical formulations.

2. Chamomile’s Calming Heritage

Apigenin is one of the key flavonoids in chamomile, a botanical with a long tradition of use for relaxation. A plant-derived ingredient that connects evening wellness formulas to chamomile’s trusted botanical heritage.

3. Cellular Wellness Support

Studied for interactions with cellular signaling pathways involved in oxidative balance and healthy cellular function. Supports wellness formulations around cellular health and metabolic equilibrium.

4. The Flavonoid Family Effect

Complements quercetin, luteolin, and kaempferol in broad-spectrum botanical formulas — mirroring how these compounds appear together in a plant-rich diet.

FORMULATION IDEAS
Application 1
Application 2

1. Botanical Calm Capsules

Standalone apigenin (100–200mg) positioned around chamomile’s calming heritage. The celery-and-chamomile origin story connects supplements to ingredients consumers trust from their tea cupboard.

2. Multi-Flavonoid Antioxidant Blends

Pair with quercetin, luteolin, and resveratrol for a broad-spectrum plant flavonoid complex — each bringing a different botanical origin story to the formulation.

3. Evening Relaxation Formulas

Combine with magnesium, L-Theanine, and calming herbals. Apigenin’s chamomile connection gives the formula a trusted botanical anchor consumers intuitively understand.

4. Vegan Botanical Gummies

The plant-derived phospholipid story makes apigenin a natural fit for vegan gummy formulations — where botanical origin drives premium positioning and brand differentiation.

OEM & PACKING
OEM

OEM

Certificates

CERTIFICATES

Transportation

TRANSPORTATION

Packaging

PACKAGING

FAQ

Q1: Is the apigenin in this product natural or synthetic?

The apigenin used is nature-identical — chemically identical to the apigenin naturally found in celery, chamomile, and parsley. The phospholipid carrier is sourced from plant-derived lipids. Together, they form a product compatible with vegan and clean-label botanical formulations.

Q2: Why use a liposomal format for a plant flavonoid?

Apigenin is naturally lipophilic — it doesn’t dissolve well in water, limiting its dispersibility and absorption. Liposomal encapsulation wraps apigenin within a phospholipid bilayer, improving water dispersibility and supporting gradual, sustained release. It’s a biomimetic approach — using nature’s own transport mechanism to deliver nature’s own flavonoid.

Q3: Which loading should I choose — 50% or 70%?

Both share the same liposomal platform and plant-derived phospholipid carrier. The 50% grade suits mainstream everyday-wellness positioning. The 70% grade targets premium high-potency botanical products. Using both grades enables tiered product positioning while maintaining a consistent ingredient story.


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