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L-Selenomethionine 0.5% Powder Organic Selenium Amino Acid CAS 3211-76-5 Food & Feed Grade

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Organic Selenium Amino Acid

L-Selenomethionine Powder 0.5%

Selenium is one of those trace minerals the human body cannot manufacture on its own — yet it quietly powers glutathione peroxidase, the enzyme system that defends every cell against oxidative stress. Nature’s elegant answer is L-selenomethionine: a single selenium atom slipped precisely into the backbone of the essential amino acid methionine, exactly as it appears in grains, legumes, and Brazil nuts. But here lies the paradox — pure L-selenomethionine carries roughly 40% elemental selenium by weight, a concentration far too potent for practical, safe dosing. Our answer is precision dilution: we blend purified L-selenomethionine onto a dicalcium phosphate (DCP) carrier at a standardized 0.5% ratio, bringing elemental selenium down to a safe, manageable 2,000 ppm. The result is a white to off-white fine powder engineered for microgram-accurate fortification of dietary supplements and animal feed premixes — organic selenium in its most bioavailable amino acid form, without the handling hazards of concentrated selenium compounds.

0.5% on DCP
Organic Selenium
CAS 3211-76-5
Food & Feed Grade
L-Selenomethionine Powder 0.5%

Specifications

Item Specification
Product Name L-Selenomethionine Powder 0.5%
CAS Number 3211-76-5
Molecular Formula C₅H₁₁NO₂Se
Molecular Weight 196.11 g/mol
IUPAC Name (2S)-2-Amino-4-(methylselanyl)butanoic acid
Active Loading ≥ 0.5% (≡ 5,000 ppm selenomethionine)
Elemental Selenium ≥ 0.20% (≡ 2,000 ppm Se)
Carrier Dicalcium Phosphate (DCP)
Appearance White to Off-White Fine Powder
Solubility of Active L-Selenomethionine is soluble in water; the composite powder disperses in aqueous media
Loss on Drying ≤ 5.0%
Heavy Metals (Pb) ≤ 5 ppm
Arsenic (As) ≤ 2 ppm
Mesh Size 80 – 100 Mesh
Production Method Chemical synthesis / Fermentation → Dilution on DCP carrier
Grade Food Grade / Feed Grade
Shelf Life 24 Months (store ≤ 25°C, away from light, sealed)

Elemental Journey

Selenium in Nature

From Soil to Amino Acid — Selenium’s Natural Form

Long before humans learned to fortify with selenium, plants were mastering the chemistry. In selenium-rich soils, legumes and grains absorb the mineral and guide it into methionine’s molecular framework, producing L-selenomethionine — nature’s chosen storage form of organic selenium. This is the same molecule our powder delivers, built by the same biochemical pathway that fills Brazil nuts with selenium.

What distinguishes this product from a simple mineral salt is precisely this molecular design: the selenium atom is covalently bound inside an amino acid, mirroring how the element travels through the natural food chain — a form the body recognizes, absorbs, and utilizes on familiar terms.

0.5% DCP Dilution

Why 0.5%? — The Arithmetic of Safe Dosing

Consider the numbers: pure selenomethionine is roughly 40% elemental selenium — about 400,000 ppm. A single mis-measured gram could push an entire batch past safe limits. By dispersing the active onto DCP at 0.5%, we bring selenium down to 2,000 ppm: concentrated enough for efficient formulation, dilute enough for safe, accurate microgram-level dosing.

The dilution is not an afterthought — it is the safety feature. Every 1 kg of this powder delivers exactly 2,000 mg of elemental selenium in a fully predictable, reproducible ratio, batch after batch.

Clean Chemistry — Synthesis with Precision

L-selenomethionine is produced by chemical synthesis or fermentation — selenium substituted for sulfur along the methionine pathway — then purified to high concentration by crystallization. Finally, the pure active is precision-blended with food-grade DCP to a uniform 0.5% homogeneity across the entire lot.

Every batch is verified by ICP-MS or AAS for total selenium content and by HPLC for selenomethionine identity, so the specification you approve is exactly the specification you receive.

HALAL
ISO 9001
ISO 22000
COA
MSDS

Product Highlights

Se-for-S

Seleno-Amino Acid Design

One atom makes the difference: L-selenomethionine differs from methionine by a single selenium-for-sulfur substitution. It is the dominant organic selenium species in plant and animal foods — chemically distinct from inorganic salts like sodium selenite and sodium selenate.

2,000 ppm

Built-In Dosing Safety

The 0.5% DCP pre-dilution brings elemental selenium from a hazardous ~400,000 ppm down to a manageable 2,000 ppm — enabling accurate microgram-scale dosing with zero concentrated-selenium handling risk.

HPLC

A Defined, Traceable Species

A single, chemically defined molecule with a unique chromatographic retention time — analytically distinguishable from selenium yeast’s undefined mixtures and fully traceable from batch to batch.

DCP

Premix-Ready Carrier

Dicalcium phosphate is the industry-standard premix excipient — free-flowing, compatible with other vitamins and minerals, and stable alongside co-formulated micronutrients through shelf life.

Certificate of Analysis (COA)

Product Name L-Selenomethionine Powder 0.5% Batch No. DMT20260715
CAS No. 3211-76-5 Test Date 2026-07-15
MFG Date 2026-07-10 Expiry Date 2028-07-09
Items Specification Methods Results
Assay (SeMet) ≥ 0.5% HPLC 0.52%
Total Selenium ≥ 0.20% ICP-MS / AAS 0.21%
Appearance White to Off-White Fine Powder Visual Conforms
Loss on Drying ≤ 5.0% Gravimetric 2.8%
Heavy Metals ≤ 10 ppm ICP-MS Conforms
Lead (Pb) ≤ 5.0 mg/kg ICP-MS Conforms
Arsenic (As) ≤ 2.0 mg/kg ICP-MS Conforms
Total Plate Count ≤ 1000 cfu/g Plate Count Conforms
Yeast & Mold ≤ 100 cfu/g Plate Count Conforms
E. coli Negative / 25g USP <62> Conforms
Salmonella Negative / 25g USP <62> Conforms
Shelf Life 24 months from production date. Refer to the batch-specific COA for exact expiry.
Storage Store in a cool, dry, dark, sealed container below 25 Deg C. Keep away from light and moisture.

Function & Wellness Benefits

A

Selenium in Nature’s Own Form

Selenium is delivered as an amino acid-bound organic molecule — the identical form the element takes inside whole foods. For formulators, this means a raw material that matches how the body already handles selenium from the diet, rather than an inorganic salt the body must process differently.

B

Supports Cellular Antioxidant Defense

Selenium is the structural core of glutathione peroxidase, the enzyme family that neutralizes peroxides and shields cell membranes from oxidative damage. Supplementing selenium supports this endogenous defense system — the body’s own daily maintenance crew.

C

Contributes to Normal Immune Function

Selenium plays a documented role in the normal functioning of the immune system and the thyroid gland. As a key mineral in the daily nutrient picture, it supports the physiological processes consumers increasingly look for in their supplements.

D

Precise, Repeatable Dosing

With selenium standardized at 2,000 ppm on a uniform DCP carrier, every gram delivers the same measurable selenium dose. Formulators gain predictable label-claim support, and premix manufacturers gain a blend they can repeat with confidence.

Applications

Dietary Supplement
Feed Premix

Dietary Supplement Premixes

Multi-mineral and multi-vitamin/mineral tablets, capsules, and powders with label-declared selenium — the organic amino acid form preferred where bioavailability and clean-label sourcing matter.

Animal Feed Premixes

Livestock, poultry, and aquaculture feed premixes where organic selenium is specified — providing the trace mineral in the form animals absorb most efficiently.

Food Fortification

Formulated nutritional products, powdered beverages, and fortified foods developed under applicable selenium fortification regulations — with a predictable, documentable selenium contribution per serving.

Nutraceutical Blends

Integrated multi-nutrient premises where selenium must be combined with vitamins, minerals, and botanicals — the DCP carrier blends cleanly without interfering with co-formulated actives.

Clean-Label Formulations

For brands positioning around organic, amino-acid-bound minerals — a single defined species with full analytical documentation, standing in contrast to undefined yeast-based selenium products.

Professional Supply Chain & Services

Quality Certs

Quality Certifications

Full documentation including COA, MSDS, and TDS. HALAL, ISO 9001, ISO 22000 — compliant with global market standards.

OEM

Custom OEM/ODM

Tailored formulation, blending, tablet compression, capsule filling, and private-label manufacturing for your brand requirements.

Packaging

Secure Packaging

Foil bags, fiber drums, and customized packaging with nitrogen flushing and light protection for product stability.

Logistics

Fast Global Delivery

Reliable logistics network with temperature-controlled shipping options to ensure product integrity upon arrival.

Frequently Asked Questions

What sets L-selenomethionine apart from sodium selenite?
+

The chemical architecture is fundamentally different. L-selenomethionine (C₅H₁₁NO₂Se) is an organic amino acid with selenium covalently bonded inside its structure, while sodium selenite (Na₂SeO₃) is an inorganic salt carrying selenium as a selenite anion. Organic amino acid-bound selenium is the form the body encounters naturally in food — a distinction formulators can document on their labels.

Why offer a 0.5% dilution instead of the pure compound?
+

Pure selenomethionine contains roughly 40% selenium — about 400,000 ppm — a concentration where even small weighing errors can exceed safe limits. The 0.5% DCP dilution brings selenium to 2,000 ppm, allowing accurate microgram-scale dosing while eliminating concentrated-selenium handling hazards. The dilution IS the safety mechanism.

How is the 0.5% concentration verified?
+

Every batch undergoes dual verification: total selenium is quantified by ICP-MS or AAS after acid digestion, and selenomethionine identity is confirmed by HPLC against a certified reference standard. Both tests are run on every batch before release, with full COA documentation provided.

How does this compare with selenium yeast?
+

Selenium yeast grows in a selenium-enriched medium and yields a variable mixture of selenomethionine, selenocysteine, and other uncharacterized selenium species — none individually quantified. Our powder contains one single, chemically defined selenium species at a precisely controlled concentration, delivering batch-to-batch consistency that undefined yeast preparations simply cannot match.


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