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High Absorption Liposomal Vitamin B1 Powder Thiamine Hydrochloride Liposome Liposomal Thiamine HCl CAS 67-03-8 Bulk Supply

Short Description:

Liposomal Vitamin B1 (Thiamine Hydrochloride Liposome) is an advanced nutrient delivery system designed to optimize the bioavailability and stability of water-soluble Thiamine HCl. Standardized as a fine, pale yellow powder, it is available in two highly concentrated active loading capacities: 50% and 70%. Traditional Vitamin B1 is highly susceptible to heat degradation, gastric acid destruction, and exhibits a strong, characteristic metallic odor that limits its formulation versatility. By encapsulating Thiamine HCl within protective nano-sized lipid bilayers, this product effectively shields the active molecule, neutralizes its raw odor, and facilitates superior cellular absorption, making it an exceptional technical raw material for high-end formulations.


Product Detail

Product Tags

Advanced Nutrient Delivery

LIPOSOMAL VITAMIN B1

50% / 70% LOADING POWDER

Liposomal Vitamin B1 (Thiamine Hydrochloride Liposome) is an advanced nutrient delivery system designed to optimize the bioavailability and stability of water-soluble Thiamine HCl. Standardized as a fine, pale yellow powder, it is available in two highly concentrated active loading capacities: 50% and 70%. Traditional Vitamin B1 is highly susceptible to heat degradation, gastric acid destruction, and exhibits a strong, characteristic metallic odor that limits its formulation versatility. By encapsulating Thiamine HCl within protective nano-sized lipid bilayers, this product effectively shields the active molecule, neutralizes its raw odor, and facilitates superior cellular absorption, making it an exceptional technical raw material for high-end formulations.

CAS 67-03-8
50%/70% Loading
Odor Masked
Liposomal Vitamin B1 Powder

Technical Specifications
Botanical Name / Aliases
Thiamine Hydrochloride Liposome / Liposomal Thiamine HCl
Part Used
N/A (Synthetic / Technical Bio-Synthesis)
Appearance
Fine, pale yellow to off-white powder
Active Loading Capacity
50% / 70%
CAS No.
67-03-8 (Active Thiamine HCl)
Molecular Formula
C12H17ClN4OS·HCl (Active Ingredient)
Mean Particle Size
80nm – 130nm
PDI (Polydispersity Index)
≤ 0.25
Encapsulation Efficiency
≥ 90%
Zeta Potential
-25mV to -35mV
Testing Method
HPLC (for Active Assay), DLS (for Particle Size & PDI)
Grade
Food Grade / Technical Grade
Certificates
ISO, HACCP, Halal, Kosher
Shelf Life
24 Months
Storage Conditions
Store in a cool, dry place away from direct light, heat, and moisture

Liposomal Technology

Liposomal technology is a premier micro-encapsulation delivery system that utilizes phospholipid bilayers—structured identically to human cell membranes—to encapsulate active ingredients such as Thiamine Hydrochloride into nano-sized spherical vesicles. This biomimetic structure significantly enhances the solubility and stability of active compounds, protecting the active core from oxidative degradation and gastric acid. By mimicking natural cell membranes, liposomes facilitate direct cellular integration and lymphatic absorption, bypassing traditional metabolic barriers to achieve vastly superior bioavailability compared to conventional raw powders.

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Key Highlights

Excellent Odor Masking

Standard Thiamine HCl possesses a sharp, unpleasant sulfur-like odor. Our liposomal encapsulation completely traps the active molecules within lipid cores, neutralizing the metallic taste and smell for seamless integration into powder mixes.

Exceptional Bioavailability

Nano-sized spheres (80-130nm) facilitate direct uptake via lymphatic pathways, avoiding standard intestinal transporter saturation.

Enhanced Thermal & Acid Stability

The lipid bilayer acts as a physical barrier, shielding Thiamine HCl from degradation during processing heat and exposure to low-pH gastric environments.

High Active Concentrations

Offering 50% and 70% active loading capacities, enabling formulators to deliver robust nutritional payloads with minimal excipient volume.

Evidence & Certificates

1. TEM Micrograph: Structural validation of spherical, well-formed bilayer liposomes available upon technical request.

2. Particle Size Distribution (DLS): Batch-specific Dynamic Light Scattering reports verifying uniform particle distribution under 130nm and PDI ≤ 0.25.

3. Encapsulation Efficiency (EE%): Proven HPLC assay reports validating that ≥ 90% of the active Thiamine HCl is securely encapsulated within the liposome matrix.

4. Comprehensive Certificate of Analysis (COA): Full chemical and microbiological profiling accompanying every commercial shipment.

Functional Roles
Functional Roles

Coenzyme Energy Support

Delivers highly bioavailable Thiamine, a crucial coenzyme in the citric acid cycle, supporting efficient carbohydrate metabolism and ATP generation.

Nervous System Structural Maintenance

Facilitates the systemic transport of Thiamine necessary for maintaining cellular membrane integrity and standard neural wellness.

Systemic Bioavailability Optimization

Bypasses conventional rate-limiting absorption steps, maximizing intracellular thiamine levels.

Cellular Defense Assistance

Protects the bio-active molecules from premature breakdown, ensuring sustained nutrient delivery to target tissues.

Industry Applications
Application
Application

Standardized Dry-Blend Formulas

Ideal for premium powder formulations, meal replacements, and functional premixes requiring complete taste-masking of B-vitamins.

Solid Dose Compression

Highly suitable for technical wellness tablets and capsules seeking compact dosing via 70% high-loading powder.

Functional Food Systems

Incorporated into nutritional bars, fortified cereals, and baked goods requiring elevated thermal stability during processing.

Advanced R&D Formulations

Used as a highly bioavailable reference standard in academic and industrial delivery-system research.

Professional Supply Chain & Services
Industrial Packaging

Industrial Packaging

Standardized bulk delivery in 1kg vacuum aluminum foil bags and 25kg double-lined fiber drums.

Custom Formulation Support

Custom Formulation Support

Customization of particle size and dispersion rates tailored to specific formulation viscosity and moisture requirements.

High-Load OEM

High-Load OEM

Private-label bulk supply utilizing our proprietary 50% and 70% ultra-high loading technologies to optimize final production costs.

Common Questions
Q1: How does Liposomal B1 resolve the strong odor associated with Thiamine HCl?
A: The sulfur-like metallic odor of Thiamine HCl is caused by free molecules reacting with moisture and air. By encapsulating Thiamine HCl entirely within the core of phospholipid bilayers, the active molecules are physically isolated from sensory receptors, completely masking the taste and smell.
Q2: What is the technical difference between 50% and 70% active loading?
A: 50% loading provides an optimized balance of lipid carriers and active ingredients, offering excellent dispersion in aqueous applications. 70% loading is a highly concentrated format designed specifically for space-constrained formulations (like multi-ingredient capsules or tablets), reducing the required dose size by 40% compared to standard liposomes.
Q3: Can Liposomal B1 powder withstand thermal food processing?
A: Traditional Thiamine HCl degrades rapidly when exposed to baking or pasteurization heat. The lipid bilayer of our liposomes provides structural insulation, significantly reducing thermal degradation rates compared to unencapsulated B1.

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