Products
Food Grade High Absorption Liposomal Melatonin Powder Pure CAS 73-31-4 Natural Sleep Aid Support Clean Label Vegan
LIPOSOMAL MELATONIN
Powder (50% / 70%)
Liposomal Melatonin Powder combines nature-identical Melatonin (CAS 73-31-4) — the same molecule your body naturally produces to regulate its daily rhythm — with a plant-derived phospholipid carrier for gentle, targeted delivery. Offered in 50% and 70% active concentrations, this ingredient is designed for formulators creating nighttime wellness products: sleep-support gummies, calming herbal blends, bedtime functional drinks, and holistic evening rituals. The liposomal shell is built from non-GMO sunflower or soy lecithin, giving your formula a plant-based delivery edge.
Plant-Derived Phospholipids
Clean Label
Non-GMO
Technical Specifications
| Item | Data |
| Product Name | Liposomal Melatonin Powder |
| Active Ingredient | Melatonin (CAS 73-31-4), Nature-Identical |
| Active Loading Capacity | 50% / 70% |
| Encapsulation Efficiency (EE%) | ≥ 88% (Typical) |
| Particle Size (Typical Range) | 80nm – 250nm (Rehydrated) |
| PDI (Polydispersity Index) | ≤ 0.35 |
| Appearance | White to Slightly Yellow Powder |
| Solubility | Dispersible in water (forms stable liposomal suspension) |
| Loss on Drying | ≤ 5.0% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Phospholipid Source | Non-GMO Sunflower / Soy Lecithin (Grade Dependent) |
| Dietary Compliance | Suitable for Vegan / Vegetarian Formulations |
| Storage Condition | Cool, dry environment; sealed container protected from light |
| Shelf Life | Refer to batch-specific COA |
Liposomal Delivery Principle
Your body already knows melatonin — it produces it every evening as daylight fades. The challenge isn’t the molecule itself; it’s how to deliver it in a way that mirrors the body’s natural rhythm: gentle, gradual, and well-tolerated by the digestive system.
Conventional melatonin powders dissolve poorly and can pass through the GI tract unevenly. Our liposomal approach wraps each melatonin molecule within a phospholipid bilayer — the same type of lipid structure that forms your own cell membranes. When consumed, these tiny vesicles (80–250 nanometers) protect the melatonin through the stomach environment and support steady, sustained release in the intestinal tract. For formulators, this means you can create nighttime products that feel as natural as the sleep they support — gummies, oral sprays, bedtime tonics, and herbal sleep blends — all powered by a delivery system that works with the body, not against it.
Key Advantages
Nature-Identical Active, Plant-Derived Phospholipid Shell
The melatonin molecule is nature-identical to the endogenous hormone; the liposomal phospholipid shell is sourced from non-GMO sunflower or soy lecithin. This plant-derived carrier layer makes the delivery system compatible with vegan, vegetarian, and clean-label formulations.
Gentle, Sustained Release Profile
Unlike immediate-release powders that deliver melatonin in a single spike, the liposomal bilayer supports a gradual release pattern — more closely mimicking the body’s own natural melatonin secretion curve, a feature valued by premium wellness brands.
Unlocks Creative Dosage Formats
Liposomal encapsulation transforms poorly water-soluble melatonin into a water-dispersible ingredient, opening the door to bedtime gummies, oral sprays, functional beverages, herbal tincture blends, and sublingual formats — far beyond traditional tablets.
Light-Protected Stability
The phospholipid bilayer naturally shields the light-sensitive melatonin molecule, helping maintain potency from production through the final product’s shelf life — without relying on synthetic stabilizers or opaque packaging alone.
Evidence & Lab Verification
1. HPLC Active Assay
Each batch is verified via HPLC for accurate melatonin loading, ensuring your formula delivers exactly what your label claims.
2. DLS Particle Size Verification
Dynamic light scattering confirms that vesicles fall within the 80nm–250nm range — the optimal size window for intestinal absorption and gentle release.
3. Encapsulation Efficiency Confirmation
EE% ≥ 88% confirms that melatonin is genuinely encapsulated within liposomes, not merely surface-blended — a distinction that matters for brands marketing true liposomal delivery.
4. Clean-Label Compliance Screening
Heavy metals, microbial limits, and solvent residues are rigorously tested to meet EU and North American dietary supplement safety standards — supporting your brand’s clean-label positioning.
Functional Roles
1. Natural Sleep Rhythm Support
Melatonin is the body’s own “evening signal” — a molecule your pineal gland releases as light fades. Supplementing with nature-identical melatonin helps support the body’s natural transition toward restful sleep, especially for those with irregular schedules, screen-heavy evenings, or age-related melatonin decline.
2. Antioxidant Nighttime Defense
Melatonin is also a potent, broad-spectrum antioxidant that directly neutralizes free radicals. Unlike many daytime antioxidants, melatonin works while you rest — making it a unique dual-action ingredient for overnight cellular renewal and skin-beauty-from-within formulations.
3. Gentle Jet Lag & Travel Wellness
For brands serving frequent travelers, melatonin offers a well-recognized, consumer-trusted option for supporting the body’s adjustment to new time zones — ideal for travel wellness kits, airport retail supplements, and lifestyle subscription boxes.
4. Versatile Formulation Partner
Liposomal melatonin blends beautifully with calming botanicals — chamomile, lemon balm, passionflower, L-theanine, magnesium — enabling sophisticated multi-ingredient nighttime complexes that tell a richer product story.
Applications
1. Bedtime Gummies & Soft Chews
The water-dispersible liposomal format is ideal for sleep-support gummy formulations — a fast-growing category in the natural supplement space, popular with younger consumers and those seeking pill-free alternatives.
2. Oral Sprays & Sublingual Drops
The fine particle size (80–250nm) and phospholipid compatibility make liposomal melatonin well-suited for oral spray and sublingual delivery formats — offering rapid absorption perception that resonates with premium wellness positioning.
3. Herbal Nighttime Tea Blends & Functional Beverages
Water-dispersible liposomal powder dissolves cleanly into hot or cold beverages, enabling sleep-support functional teas, bedtime lattes, calming cocoa mixes, and relaxation tonic drinks.
4. Holistic Evening Wellness Kits
Paired with magnesium, adaptogenic herbs, and soothing botanicals, liposomal melatonin serves as the anchor active in curated evening ritual kits — a growing trend in direct-to-consumer wellness brands and boutique apothecary lines.
OEM & Packing
FAQ
Q1: Is the phospholipid source plant-based? Can it support vegan certification?
Yes. Our standard liposomal melatonin uses non-GMO sunflower lecithin as the phospholipid source, making it suitable for vegan and vegetarian product lines. Soy lecithin options are also available upon request.
Q2: Can I use this ingredient in a bedtime gummy formulation?
Absolutely. The water-dispersible liposomal powder integrates well into gummy bases, and the phospholipid encapsulation helps protect melatonin from heat degradation during the gummy cooking and setting process.
Q3: What is the recommended serving size for a sleep-support product?
Serving size depends on your target market’s regulatory framework and product positioning. As a B2B ingredient supplier, we provide the raw material with verified active loading (50% or 70%); you determine the final dosage based on your formulation, target region regulations, and label strategy.
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