Products
Health Postbiotic Supplements Pasteurized Akkermansia Muciniphila Powder 100B–2000B TFU/g Akkermansia Postbiotic Powder
Next-Gen Postbiotic Ingredients
PASTEURIZED
AKKERMANSIA MUCINIPHILA (POSTBIOTIC)
Akkermansia muciniphila is a gut bacterium (phylum Verrucomicrobia) naturally present in the human intestinal microbiota. This product is a pasteurized, freeze-dried whole-cell postbiotic powder produced via controlled fermentation followed by thermal inactivation — quantified at ≥ 100 billion TFU per gram. Pasteurized A. muciniphila received EFSA Novel Food authorization (2021) for food supplements, with individual strains cleared through U.S. FDA NDI notification. Supplied as a bulk raw material for dietary supplement and functional food manufacturers.
EFSA Novel Food
No Cold Chain
TECHNICAL SPECIFICATIONS
EVIDENCE & CERTIFICATES
1. EFSA Novel Food 2021 Approved
Pasteurized Akkermansia muciniphila obtained official EFSA Novel Food authorization, with corresponding US FDA NDI notification for global supplement market sales.
2. Strict Batch TFU Quantification Test
Each batch adopts flow cytometry TFU detection, accurately count total inactivated cells to guarantee ≥100B TFU/g stable potency.
3. Full Batch COA & Safety Test Report
Complete heavy metal, microbial, moisture test documents provided per batch, fully compliant with EU & US food supplement standards.
PRODUCT HIGHLIGHTS
Pasteurized Postbiotic — Heat-Inactivated Whole Cells
The product undergoes thermal pasteurization after fermentation, rendering the bacterial cells metabolically inactive while preserving their whole-cell structural components. This pasteurized form is the same product category authorized by EFSA as a Novel Food (2021) and cleared through U.S. FDA NDI notification for multiple commercial strains. Pasteurization eliminates the need for cold-chain logistics during storage and transport.
Freeze-Dried Powder — Ambient Temperature Stability
Post-pasteurization lyophilization converts the inactivated biomass into a dry, flowable powder stable at ambient temperatures (15–25°C). No refrigeration or frozen storage is required, reducing supply chain complexity for international B2B distribution and simplifying warehousing for finished product manufacturers.
Quantified by TFU — Applicable Enumeration for Inactivated Cells
Standard CFU counting measures only viable, culturable bacteria. For pasteurized whole-cell products, TFU enumeration via flow cytometry provides a direct count of total inactivated bacterial cells present, offering a reliable and batch-consistent potency specification for quality control.
Controlled Fermentation and Inactivation
The production strain is cultivated under controlled, axenic fermentation conditions. Each batch undergoes verified thermal inactivation with post-process sterility confirmation, ensuring the absence of residual viable A. muciniphila cells in the final powder.
FUNCTIONAL ROLES
1. Gut Barrier Integrity Support
The inactivated whole-cell components contribute to maintaining the protective mucus layer and tight junction structure of the intestinal epithelium.
2. Metabolic Health Modulation
Supports balanced metabolic pathways associated with healthy body weight management and glucose homeostasis.
3. Formulation Versatility
The ambient-stable, flowable powder integrates into capsules, tablets, powder sachets, and functional foods without cold-chain constraints.
4. Batch-Consistent Potency
TFU-based enumeration via flow cytometry ensures reliable, reproducible cell count from batch to batch for precise formulation dosing.
INDUSTRIAL APPLICATIONS
1. Dietary Supplement Manufacturing
Bulk raw material for encapsulation into capsules, tablet compression, or powder sachet filling — intended for adult food supplement formulations.
2. Functional Food Product Development
Ingredient for formulated functional foods, including powdered beverage mixes, meal replacement formulations, and nutritional bar applications where postbiotic inclusion is specified.
3. Synbiotic & Multi-Strain Formulation
Compatible with other probiotic strains (e.g. Lactobacillus, Bifidobacterium species) and prebiotic fibers in multi-ingredient supplement blends, subject to individual formulation stability testing.
4. Contract Manufacturing & Private Label
Bulk powder supply for contract manufacturers producing finished dietary supplement products under private label or contract-fill arrangements.
OEM & PACKING
TECHNICAL FAQ
Q1: Why is this product pasteurized rather than a live probiotic?
A: Pasteurization eliminates the need for cold-chain logistics and dramatically improves formulation stability, as the product does not require a protective matrix or controlled storage to maintain viability. In the EFSA Novel Food authorization (2021), the pasteurized form was specifically recognized as safe for food supplements, and the whole-cell components drive the intended biological activity without requiring living bacteria.
Q2: What is the difference between TFU/g and CFU/g?
A: CFU counts only viable, replicating cells grown on agar plates. For pasteurized products, CFU is not applicable because cells are inactivated. For pasteurized products, TFU enumeration via flow cytometry directly enumerates all bacterial cells — live or inactivated — providing the correct potency measurement for this postbiotic ingredient.
Q3: Does this product require refrigerated storage or shipping?
A: No. The freeze-drying and pasteurization process renders the powder stable at ambient temperatures (15–25°C). No cold chain is required for storage or international transport, significantly reducing logistics costs compared to live probiotic ingredients.
