High-Purity Silybin (Silibinin) Powder Isolate | Standardized Milk Thistle Seed Extract
Rising Demand for Plant-Based Antioxidants in Global Functional Ingredient Markets: Our High-Purity Silybin (Silibinin) Powder Isolate Sets a New Benchmark for Quality and Consistency
Meeting the Market Where Precision Matters
As consumer interest in clean-label, plant-derived functional ingredients continues to accelerate across North America and Europe, the demand for standardized botanical extracts with verifiable purity profiles has reached an inflection point. Among the most sought-after materials in the nutraceutical and functional food supply chain is Silybin (Silibinin), the primary bioactive constituent of Silybum marianum (Milk Thistle) seed extract — now available in industry-leading specifications of ≥95% and ≥98% purity from our production facility.
For B2B buyers in the dietary supplement, functional food, and cosmetic industries, sourcing ingredients with consistent, analytically verified specifications is no longer optional — it is the baseline expectation. Impurity variation and batch-to-batch inconsistency remain persistent pain points in the botanical extract supply chain. Our Silybin (Silibinin) Powder Isolate is produced under a rigorous multi-stage purification protocol that combines chromatographic separation and controlled crystallization, yielding a fine off-white powder with tight limits on residual solvents, heavy metals, and related flavonoids — parameters that formulators and quality assurance teams require for seamless downstream integration.
Each batch is released against a Certificate of Analysis (CoA) that includes HPLC quantitation, microbial testing, pesticide screening, and heavy metal panels — documentation that supports compliance with US FDA 21 CFR Part 111 (cGMP for Dietary Supplements) and EU Directive 2002/46/EC requirements for food supplement ingredients.
Technical Snapshot
| Parameter | Specification |
|---|---|
| Active Marker | Silybin A + Silybin B (Silibinin) |
| Purity Grades Available | ≥95% / ≥98% by HPLC |
| Appearance | Off-white to pale yellow powder |
| CAS Number | 22888-70-6 (Silibinin) |
| Solubility | Sparingly soluble in water; soluble in ethanol, acetone |
| Typical Applications | Tablet/capsule formulations, powdered drink mixes, topical preparations |
| Regulatory Status | GRAS-notified uses; pre-market notification not required for this ingredient category under current US/EU frameworks |
A Strategic Sourcing Partner for Global Formulators
The global functional ingredient market is projected to grow at a compound annual rate exceeding 8% through 2030, with botanical antioxidants ranking among the fastest-growing sub-segments. In this environment, supply chain reliability and regulatory compliance are as critical as the ingredient itself.
We invite dietary supplement manufacturers, functional food producers, and cosmetic ingredient buyers to connect with our technical and commercial team to discuss specification customization, pilot batch availability, and long-term supply arrangements.
We provide high-purity Silybin (Silibinin) Powder Isolate at 95% and 98% specifications, sourced from standardized Milk Thistle seed extract, with full analytical documentation and regulatory compliance support for US and EU markets. Contact us today to learn more about pilot batch availability and tailored specification options.
Post time: Apr-22-2026




